Blog Archives

Hi All –

Here is a recent case study from my practice.

Forty-two year old woman with chief complaints of 10 years of IBS and fatigue, now heading into depression and anxiety. She has constant sweet cravings, has gained some weight and was at the end of her rope, feeling like her body was failing her already, and now her mind was starting to be dragged down with it.

I did my two basic tests that I use with every new patients, an adrenal stress profile and a GI pathogen screen. You can see from her adrenal test she was very low in cortisol and DHEA with a total cortisol of 11 (when ideal is around 35-40) and a DHEA of 1.99 (ideal should be an 8). I used liquid pregnenolone at 15 drops 3x day, liquid DHEA at 2 drops 3x day (from Biomatrix) and a broad spectrum multi vitamin (any good one will do) along with blood sugar control nutrients (Glucomend from Douglas Labs).
Her Energy levels increased by week three of the program. Looking at her GI pathogen screen (401H from Biohealth) we found cryptosporidium AND giardia. What a combination. After all these years of practice you think you’ve seen everything and then boom, one patient with these two bugs. Pretty incredible. Had to write about it. Either one of these infections I’ve seen debilitate hundreds of patients, but to have both? at the same time?
Anyhow, this was a home run for sure this patient was destined to get better. We did a combined anti-biotic and herbal protocol using Alinia prescribed by her MD along with: Artemesia annual 500mg 2 capsules 3x day (Thorne Research or Allergy Research Group), Oregano Oil Extract 2 tablets 3x day (Designs for Health or Biotics Research) and Morinda Supreme, 2 capsules 3x day (Supreme Nutrition).
Worked like a charm, we just spoke this week and her GI symptoms are gone gone gone. Her energy is up to normal and she quite literally feels like a new person, wondering how she got through this haze of the last ten years of being sick. Functional Medicine works! It does not need to be complicated. You will always been successful if you just start of with a basic adrenal and GI test and go from there.  You will always been successful if you just start of with a basic adrenal and GI test and go from there.

Here is Sean’s announcement, should be a good one!


TONIGHT, fellow brainiac Dr. Daniel
Kalish returns to UW Radio to discuss
Mind Mapping: The New Science of 
Balancing the Brain. Topics will include:
* How a natural Mind Mapping approach
differs from the pharmaceutical model.
* If it is possible to heal the brain like a
broken bone.
* Alternatives to antidepressants and
ADHD medications.
* How this new brain science impacts
weight loss.
* How Mind Mapping can help with food
and alcohol cravings.
I’m calling my shot! This show is guaranteed
That’s TONIGHT at 5pm PT/8pm ET.
Listen LIVE by internet HERE

I spent Saturday this week at Melissa and Dallas Hartwig’s nutrition seminar, one of the best classes I have attended on nutrition – ever. They both teach in masterful ways, entertaining, funny and yet completely science and research based, not an easy feat to accomplish. Their materials are better and more up to date than any nutrition course I have attended and I highly recommend their work. Please check out their website and pre-order their new book which will be released very soon so you can update your understanding of food and nutrition and take one more step towards improving your health.



I am so excited about the release of my upcoming book about Mind Mapping and The Kalish Method (tentative release: May 2012). It has been an incredible exercise for me, and I feel that it will be a valuable learning tool for both patients looking for health tips, and practitioners looking to refine their skills. Over the next few weeks, I will share some excerpts from the book. Here is the first one. Enjoy…

Introduction to the Kalish Method

“Why do I feel so crummy, Doc?”

Fat, Fatigue and Depressed: The Modern Epidemic

Fat, fatigued and depressed, what are you going to do about it? Go on a diet, chug a five hour energy drink and pop an antidepressant? Over 62% of Americans are overweight. There are 21 million people suffering from depression in our country and the numbers suffering from both weight gain and depression increase every year. Something must be done. If these statistics are accurate then there’s a good chance most of you suffer from one or more of these problems. And, the odds are, if you’re reading this blog, you’ve already realized standard medicine can do very little for you.

Taken together there are five health problems that I deal with in my clinic every day. I call them the “Big Five”: weight gain, fatigue, depression, digestive problems and female hormone imbalances. These issues have become accepted as part and parcel of modern American. In fact, many people have given up hope that they will ever feel better. I started this blog so that you can learn that there is indeed hope. Leading health practitioners are employing curative methodologies that were simply unavailable to us as recently as ten years ago. No matter how bad you’ve been feeling, or how long you’ve been feeling that way, there are options. You can feel better.

Weight gain

If you struggle with weight gain, have tried various diets, and failed repeatedly to reach your weight-loss goals? Most likely, you suffer from a damaged fat-burning metabolism. If your metabolism is broken, you will store body fat regardless of how much, or what, you eat. Cravings for sweets or carbs, overeating, and skipping meals, all contribute to a damaged metabolism. Trying to lose weight by following fad diets that restrict calories will allow you to lose weight, temporarily, and then as soon as you eat normally again, your broken metabolism will put the pounds right back on, and then some.

The more times you have gained and lost weight, the more likely you have damaged your metabolism. That will keep you from losing weight permanently until you repair your metabolism. Many past medical solutions for weight loss such as diet pills and liquid diets make people worse. Fortunately, there is a bright spot in this bleak picture. You can test and correct your metabolism. By measuring the key hormone – cortisol – your health professional can figure out how beat up your fat burning system is and what you’ll need to do to mend it…



Hi All –

OK, get this, last week I was wandering around Chicago on the most spectacular day you can imagine (see photo below), recovering from an intense brain seminar I just attended, and I wander into the world famous Field Museum. The very first exhibit I walk into I’m confronted with a big plaque, “You were built to be a hunter gatherer” (photo) Wow! Must be true it’s the Field friggin museum!

Then in the next room it gets even better, right out of a Michael Pollan book, the anthropology writer continues to wax poetic about early tribes from a few thousand years ago, “Corn diets and close quarters created health problems.”  Of course they are talking about the dawn of the Americas, when grains were being grown for the very first time, but can you believe it? Now we’ve reinvented the same problem with corn syrup, and overcrowding in large buildings – to a degree which our native ancestors could not have possibly comprehended when they were all crammed into a hut eating a corn tortillas.

Anyhow, there’s nothing new under the sun, just repeating the same old cycles. The move to agriculture was bad enough, but the move to processed food was literally cultural suicide.

Eat some meat or go workout really hard.

Talk to you soon!

-Dr. Dan

I was in Chicago this weekend at brain conference.  Check out for details about this work. I’ll be teaching a comprehensive three month course on this subject through Kalish Research in September. I believe the Organic Cation Transporter testing is the biggest breakthrough in neuroscience of our generation, and now, for the first time, we can take a snap shot of the brain and accurately measure serotonin and dopamine.  AND, more importantly, through transporter testing, we can reset neurotransmitter levels so the brain functions normally.

Marty Hinz, MD has published a dozen or so papers on this work, which are at,
time to let the world know about this scientific advance.

Hi All – 


I returned from y trip to Austin, Texas, and while a few thousand rock bands were playing background music at the SXSW music festival, I was hunkered down for three amazing days at the conference.

Presenting on three mastermind panels I spoke about hormone balancing, lab testing and the like. My featured talk was on “Mind Mapping” the new science of amino acid therapies for brain related disorders.

I met some incredible people, too many to mention but including (in the order in which I met them!) Angelo Coppola from, Jack Kruse, MD, Joe Johnson, and Melissa and Dallas Hartwig of

This is the most solid group of people I can imagine, focused on changing our lives through eating better food. Regardless of your age or type, height or religion or who you might be voting for at the upcoming presidential election you can all go Paleo and not look back. Think of it as gluten free Plus.

And if you want to lose weight and you haven’t taken a cold shower in a while then check out Dr. Kruze’s blog and apply his cold therapy ideas, I’ve lost two pounds of body fat in one week without changing anything else but using cold therapy, don’t worry you get to like it after a bit.

More to come…

Dr. Dan Kalish

Hi All,
I just returned from my trip to Austin, Texas and while a few thousand rock bands were playing background music at the SXSW music festival I was hunkered down for 3 days of the conference.
Presenting on three mastermind panels I spoke about hormone balancing, lab testing and the like. My featured talk was on “Mind Mapping” the new science of amino acid therapies for brain related disorders.
I met some incredible people, too many to mention, including (in the order in which I met them!) Angelo Coppola from, Jack Kruze, MD, Joe Johnson, and Melissa and Dallas Hartwig of
This is the most solid group of people I can imagine, focused on changing our lives through eating better food. Regardless of your age or type, height, religion, or who you might be voting for in the upcoming presidential election, you can all go Paleo and not look back. Think of it as gluten free Plus.
And, if you want to lose weight, but haven’t taken a cold shower in a while, then check out Dr. Kruze’s blog ( and apply his cold therapy ideas. I’ve lost two pounds of body fat in one week without changing anything else but using cold therapy, don’t worry you’ll get to like it after a bit…
Dr. Dan

Learning how to handle mental and emotional stress is of utmost importance. Our central nervous system, as well as our adrenal glands, can be pushed into overload by difficult life events. Mental and emotional stress can put us into a fight or flight response from which it may be difficult to recover. Fight or flight responses are generated by our sympathetic nervous system. An example of fight or flight response would be your automatic, uncontrollable response to an automobile accident.

A chronic over-stimulation of our sympathetic nervous system can lead to suppressed immunity and adrenal exhaustion. We’ll describe some of the physiological effects of mental and emotional stress and provides a few techniques for managing difficult situations.

Chronic Stress: A Daily Event

Chronic sympathetic nervous system overload is a common experience for many of us. Running out the door in the morning without eating, coffee cup in hand, getting stuck in rush hour traffic and having too much work to possibly accomplish in one day creates chronic sympathetic overload, thereby lowering our immunity. A single parent trying to juggle raising children, maintaining a home, keeping a full-time job, as well as taking care of themselves can result in sympathetic overload. We all experience these mental and emotional stressors. Are they preventable? Is there a way to get away from all significant sources of stress? Absolutely not. Our lives generate unavoidable stresses.

Responding to Stress

What we do have control over is how we respond to stress. With mental and emotional stress there is a sequence of events that determines how we will respond physiologically. It is within our conscious control to determine how these unavoidable stresses effect us on a biochemical/hormonal level. We all need to have effective means for stress reduction. It could be meditation, exercise, yoga or tai chi.

Perception, Response, Internalization

Perception, response and internalization come together to form the body’s physiological reaction to an event. First, we perceive an event. Second, we respond to that event in a positive or negative fashion. And third, we internalize the event. Internalization is where we can get stuck. If the response is negative, we may internalize the experience negatively. If our perception of the event is negative and we begin to internalize the event in a negative fashion, this internalization process can damage our nervous system and hormonal system.

As an example, imagine you are driving on the freeway and are suddenly forced off the road by a car that swerves into your lane. You barely miss being in a major accident. Typically you may have one of two responses. You may swear and curse and feel angry towards the driver who put your life in danger. In fact, you may internalize the event and be upset and angry for the rest of the day. Another possible response is to feel relief that you didn’t get hit and that no one was injured. You may suspect the other driver simply didn’t see your car or perhaps was forced to turn to avoid an obstacle on the roadway.

It’s easy to see which example would have a potential negative effect on your health. Remaining angry for a whole day doesn’t hurt anyone other than the person holding on to the anger. With a negative perception and internalization of events the physiological reaction in the body can be long lasting. The healthier psychological response carries with it fewer long-term physiological effects. The event itself will cause a stress response involving the stress hormones adrenaline, epinephrine and cortisol. A scare like this will also put your sympathetic nervous system into a fight or flight response. These responses will last only a matter of a few seconds or minutes if we don’t internalize the event negatively. After these initial responses the body will reset and normalize.

Our individual perception and internalization of life events determines the positive or negative effects they will have on our health.

Concept Shifting

Another significant mental strain on cortisol and the sympathetic nervous system is concept shifting. Concept shifting occurs when we have to change our focus or shift our attention too frequently. This can occur in a busy workplace when you are trying to complete a complicated task and you are distracted by phone calls and other interruptions. Forcing the brain to constantly shift from one subject to the next can be stressful and have a negative impact on cortisol.

Whether at work or at school, constant concept shifting will increasingly stress your cortisol levels and sympathetic nervous system. There are some positive things to be said about flexibility in thinking and being able to shift one’s attention to meet different demands. Nevertheless, your body perceives constant concept shifting as a negative stress. To the extent possible, it will benefit you to organize your schedule so that concept shifting is kept to a minimum. Since we can’t change many of the situations that require concept shifting we can counter balance the negative effects by other behaviors that improve cortisol levels and reverse sympathetic overload. This includes exercise and relaxation techniques like gentle stretching, yoga, meditation, and of course keeping our blood sugar stable!

An important lifestyle step to master is maximizing the rest and repair processes that are accomplished through adequate sleep. Although we have in many ways separated ourselves from dependence on the natural world, we are still physiologically linked to nature.


Our link to nature is clearly seen in our sleep patterns and in our hormonal system. Our hormones are intimately linked to several natural rhythms or biological clocks. These biological rhythms are based on the twenty-four hour cycle of daylight and darkness as well as the monthly cycle of the moon.


Just like the monthly biological clock in females, both men and women, have twenty-four hour cycles, or daily clocks. While fluctuations in female hormone production vary with a monthly cycle, the adrenal hormone cortisol varies with a twenty-four hour or daily cycle. Cortisol levels peak in the early morning hours as the sun rises and taper off as the sun sets, reaching their lowest levels three hours after dark. This daily rhythm of cortisol dictates when we should be our most active and when we should rest.

Any time you fly and change time zones, the importance of this twenty-four hour biological clock becomes clear. Even a time change of a few hours can be enough to throw off one’s normal sleep cycle. Cortisol not only dictates our sleep and wake states; it is also the primary hormone involved in directing immune system functioning.


Have you ever wondered why your cold or flu symptoms get worse at night? It’s because the twenty-four hour rhythm of cortisol production regulates your immune system as well. As cortisol drops at night, our immune cells become more active. These cells leave the bone marrow and spleen to protect you while you rest. During this highly active period of immune function, immune cells kill bacteria and viruses. This basic immune activity relies on appropriate levels of cortisol. As cortisol drops at night, our immune system activity picks up, killing bacteria and viruses in large numbers leading to greater mucous production. This leads to more congestion and coughing at night as your body attempts to get rid of the mucous created from destroying bacteria and viruses. At daybreak, cortisol rises and immune cells return to the bone marrow and spleen to rest and recondition in preparation for the next nightly cycle.


If cortisol is out of balance, this normal immune function is compromised. As mentioned earlier, cortisol levels rise at daybreak giving us the energy to begin the working day. As cortisol drops naturally at night, we enter into rest and recovery, physical repair and psychic regeneration. Our immune system functions optimally if we to go to sleep by 10 p.m. As we sleep, physical repair takes place, immune cells patrol our bodies, eliminating cancer cells, bacteria, viruses and other harmful agents. However, if cortisol is elevated at night this immune function is compromised. If cortisol levels are normal during sleep, then true rest and recovery takes place thereby enhancing physical repair and immunity.

During sleep we also enter into stages of psychic regeneration. During these times, the brain releases chemicals that enhance our immune system. All during the night, we are going into Rapid Eye Movement (or REM) sleep states and non-REM sleep, alternating between light sleep and deep dream states. This is how we process the mental and emotional events of the previous day and refresh our minds for the day ahead. Most people need seven to eight hours of sleep to accomplish all these tasks. Without sufficient sleep, the immune system is hard pressed to keep up with its repair work and this creates the opportunity for disease processes to begin. If you miss out on proper rest, your physical repair and psychic regeneration will be compromised.


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